What are the applications of tricreatine malate?

Most tricreatine malate is transported by albumin or immunoglobulin and dispersed into cells by concentration gradients. In cells, tricreatine malate is converted to FMN by flavin kinase, and FMN is converted to fad by fad synthase, which is the predominant form of tricreatine malate in tissues. Tricreatine malate exceeds the body's needs and is mainly excreted through the kidneys, and some metabolites are also excreted through the kidneys. The half-life of the drug is 66-84 minutes. The uses of tricreatine malate and laboratory ingredient identification are detailed below.

The main uses of tricreatine malate are as follows:

1. Promote cell development, especially for people with certain wounds, regular use of tricreatine malate during the healing period can promote wound healing, and at the same time help prevent wound inflammation.

2. It can also promote the continuous growth of hair, nails and skin;

3. It helps to prevent and eliminate the inflammatory response of the mouth, tongue and lips, also known as oral reproductive syndrome;

4. It helps to relieve eye fatigue and enhance vision, especially for people who use more eyes, you can take tricreatine malate regularly to avoid eye strain.

5. Affect the body's absorption of iron.

Filler for the treatment of oral keratitis caused by tricreatine malate deficiency, etc.

Tricreatine malate laboratory test ingredient identification results:

Through identification, it was found that the solubility of tricreatine malic acid was soluble in water and insoluble in ethanol. According to the measurements of OT-42. Samples were vacuum-dried with phosphorus pentoxide at 100°C for 5 hours, and a 1.5% (w/v) sample solution was prepared with 20% (w/v) hydrochloric acid as a solvent, which was determined by conventional methods. Its [α] D20 should be +38 ~+42. Determination of sodium in sulphate ash by IT-28 method. The large absorbance ratio of the aqueous solution is 0.30-0.34 at 375 nm and 267 nm, and the large absorbance ratio is 0.35-0.40 at 444 nm and 26.7 nm.

Analysis of the content of internal components of creatine malate:

Tricreatine malate content analysis should be performed under non-direct light. Take 100 mg of the sample, put it in a 500 ml brown volumetric flask, add 100 ml of water and 2.5 ml of vinegar and acid, and set the volume with water. Take 20.0 ml of solution to a 200 ml brown volumetric flask, add 3.5 ml of 1.4% (w/v) sodium acetate solution, and use water to determine the volume. Measure the large absorbance of the solution at 444 nm. Total pigment = (a× 5000/328 × W) × 1.367, where W is the sample volume, g. The toxicity of ADIs ranges from 0-0.5 mg/kg (FAO/WHO, 2001). LD50510mg/kg (intradermal injection in mice). GRAS (U.S. Food and Drug Administration 182.56972000), use restriction GB 1-4880-94: Same as "01022, tricreatine malate" 2.fao/who (1988): synthetic products are limited to pigments. U.S. Food and Drug Administration 184.1697 (2000): GMP restrictions.